RESUMO
No disponible
Assuntos
Humanos , Feminino , Adulto , Alérgenos/efeitos adversos , Araceae/efeitos adversos , Hipersensibilidade/etiologia , Flores , Folhas de Planta , Caules de PlantaAssuntos
Mordeduras e Picadas/diagnóstico , Mordeduras e Picadas/terapia , Peçonhas/imunologia , Peçonhas/uso terapêutico , Anafilaxia/diagnóstico , Anafilaxia/etiologia , Anafilaxia/imunologia , Anafilaxia/terapia , Animais , Mordeduras e Picadas/imunologia , Dessensibilização Imunológica/métodos , Feminino , Humanos , Imunoterapia/métodos , Pessoa de Meia-Idade , Vespas/imunologiaRESUMO
Aniseed is a spice native to the eastern Mediterranean region. Cases of simultaneous hypersensitivity to celery, mugwort pollen, and spices of the Umbelliferae family have been described as the celery-mugwort-spices syndrome. We report a case of aniseed-induced tongue angioedema. Skin prick tests to foods proved positive only to aniseed. Serum-specific immunoglobulin (Ig) E determination by enzyme allergosorbent test was 0.4 kU/L to aniseed extract and 0.6 kU/L to tare and cumin seeds. The molecular mass of the IgE-binding proteins studied by sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) immunoblotting revealed a broad IgE-binding band of 12.9-13.7 kd in aniseed and tare extract assays and a broad band of 15-17.5 kd in cumin extract. This is the first case of type I hypersensitivity due to aniseed liqueur ingestion reported. SDS-PAGE immunoblotting study showed a broad specific IgE-binding band of 12.9-13.7 kd when aniseed extract was incubated with the patient's serum; this band might correspond to the protein responsible for the described symptoms.
